The only AI scientist with a lab

Science at the
speed of AI.

Sigmatic Scout takes a research question, generates testable hypotheses, and tests them — orchestrating 300+ validated scientific tools in your lab ecosystem to return evidence. The AI scientist that acts.

Built on 20+ years of lab informatics heritage  ·  300+ scientific tools
Integrates with
Sapio
NVIDIA
Elsevier
Schrödinger
AWS
MedBioInformatics
Optibrium
+ many more

Research teams are under-resourced for the science they need to deliver.

Drug discovery teams are losing scientific time to the wrong work. The problem is not a shortage of tools. It is a shortage of capacity to act on them at the speed the work demands.

The Gap

Scientific capacity lost to coordination.

The tools and data exist. What research teams lack is the capacity to connect them at the pace the science requires. Scientific time is consumed by coordination, not discovery.

Scout

Scientific resource — at the speed of AI.

Scout handles the coordination layer — orchestrating tools, integrating lab data, and testing hypotheses — so scientists focus on the decisions only they can make.

The only AI scientist
that knows what happened at the bench.

Scout is built on the SigmaticOS orchestration layer of 300+ validated scientific tools. A scientist asks a research question. Scout generates testable hypotheses, selects and sequences the tools and data sources needed to test them, integrates context from the lab ecosystem (ELN, LIMS, data lake) and returns with evidence. Not a summary of what others have found. Science that acts.

Orchestration, not complexity
Lab-connected, by design
Prompt to endpoint
Learns your science, securely

From research question
to tested hypothesis.

Scout orchestrates the tools and data a scientist needs to test a hypothesis — automatically, traceably, and trained on the science it has already performed.

01 — Design

In silico modeling

Describe your hypothesis in natural language. Scout orchestrates structural models, docking simulations, and target analysis — you don’t need to know which tool to use.

Scout in action
“Identify the top 5 druggable targets for acquired KRAS G12C inhibitor resistance and rank by novelty and tractability.”
Molecular Docking Protein Folding Target Druggability
Scout — Design Phase
Identify druggable targets for KRAS G12C resistance…
Project RAG
Scanned 2,847 papers • 12 resistance mechanisms
1.2s
Target Druggability
Binding pocket analysis on 12 candidates
3.4s
Molecular Docking
Running docking simulations on top 5 targets…
Protein Folding
Queued — predict structures for novel targets
Agents working3 of 4 complete
02 — Make

Generate the candidate

Scout generates molecules and structures as outputs — not summaries, not ranked lists. Actionable candidates ready to move to the bench, powered by SigmaticOS.

Scout in action
“Design and optimize a protein variant of IL-6 with reduced pro-inflammatory activity but preserved receptor binding.”
Retrosynthesis BLAST Search Codon Optimization Plasmid Design Lab Automation
Scout — Make Phase
Design IL-6 variant with reduced pro-inflammatory activity…
Synthesis Request
Generated synthesis route • 4 steps • 92% feasibility
1.4s
ELN Sample Search
Found 7 related samples in notebook • 3 with assay data
0.6s
LIMS Queuing
Submitting 3 candidates to synthesis queue…
Vendor Order
Queued — check building block availability & pricing
Agents working2 of 4 complete
03 — Test

Integrate your wet lab

Scout connects to your lab ecosystem — ELN, LIMS, data lake, orchestrators — ingesting assay results and biological readouts as first-class inputs.

Scout in action
“Pull the latest CDK4 assay results from our LIMS and compare binding affinity against the previous round of candidates.”
Lab Orchestrator System ADMET Prediction Data Visualization Audit Trail
Scout — Test Phase
Compare CDK4 assay results against previous candidates…
LIMS Connector
Retrieved 128 data points from 3 assay plates
0.4s
ADMET Prediction
Running ADMET on 12 candidates…
Data Visualization
Queued — generate dose-response curves
Audit Trail
Queued — log decisions and provenance
Agents working1 of 4 complete
04 — Analyse

Learn and refine

Scout trains on the science it runs — combining computational and experimental results, sharpening across your target classes, with every decision fully traceable.

Scout in action
“Run 3 cycles of iterative compound optimization against our latest CDK4 assay data and return the top candidates for synthesis.”
ML Model Training Project RAG Data Visualization Feedback Loop
Scout — Analyse Phase
Run 3 cycles of iterative compound optimization…
Data Ingestion
Loaded 3 rounds of CDK4 assay data • 384 compounds
0.6s
ML Model Training
Retrained QSAR model on proprietary data • R² 0.91
8.2s
Feedback Loop
Cycle 3 complete • 12 candidates refined
2.1s
Data Visualization
Generating SAR heatmap and ranked output…
Agents working3 of 4 complete

Built on SigmaticOS.
20 years of lab informatics, one platform.

Scout The AI scientist you talk to
Natural language → scientific endpoints
Powered by
SigmaticOS Everything underpinning Scout — the engine that makes it possible.

In Silico Tools

300+ validated tools — docking, folding, retrosynthesis, ADMET, BLAST, codon optimization — routed automatically.

Trainable Models

Every experimental cycle sharpens the platform on your target classes and assay protocols. The more you run, the better it gets.

Traceability

Every decision logged, inspectable, and defensible. Full audit trail from hypothesis to endpoint.

Enterprise Deployment

Your data, your environment. Private cloud on NVIDIA and AWS. Nothing leaves your perimeter.

300+scientific tools
20+years heritage
100%Traceable
SOC2Type II
Lab research
Target Identification

Identify and rank druggable targets

Scout synthesizes the literature, identifies resistance mechanisms, analyses binding pockets, and ranks targets with supporting evidence.

“Identify the top 5 druggable targets for acquired KRAS G12C inhibitor resistance and rank by novelty and tractability.”
Protein structure
Protein Engineering

From question to generated construct

Scout orchestrates structure prediction, binding analysis, sequence optimization, and codon design — with your experimental history informing every step.

“Design and optimize a protein variant of IL-6 with reduced pro-inflammatory activity but preserved receptor binding.”
Molecular visualisation
Lead Identification

Generate ranked candidate molecules

Scout runs generative chemistry, docking, and ADMET prediction in a single workflow — delivering molecules ready for synthesis and bench validation.

“Generate and rank 50 novel small molecules against our CDK4/6 binding site with ADMET predictions and synthetic accessibility scores.”
Lead optimisation
Lead Optimisation

Iterative cycles that sharpen on your biology

Scout trains on your proprietary assay data, ingests experimental results, refines the model, and repeats. Your data never leaves your infrastructure.

“Run 3 cycles of iterative compound optimization against our latest CDK4 assay data and return the top candidates for synthesis.”

Scout is built for production-grade drug discovery.

Scout Academic AI Scientists
ELN/LIMS Integration ×
Organizational knowledge base (RAG) ×
Custom ML model training ×
Custom pipelines ×
Lab informatics heritage ×
Enterprise compliance ×
Agent Auditability ×

Trains on your science.
Auditable at every step.

Scout trains on the science it executes — sharpening across your target classes, assay protocols, and experimental history. Every decision is logged, inspectable, and auditable. Deployable in your environment, on SigmaticOS’s 20+ years of regulated lab informatics infrastructure.

20+
years heritage
300+
validated tools
SOC2
enterprise security

Science at the speed of AI. The only trainable AI scientist that takes your research question and tests it — with every decision fully traceable and auditable.