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Meet Scout,
Your AI Research Scientist

Ask a research question. Scout runs the in silico science so you can explore more, fail earlier, and validate the best hypotheses with Lab-in-the-Loop.

FREE 30 DAYS · Full Scout Product · No Cost During Early Access
SCOUT · AUTONOMOUS RESEARCH● LIVE
ASK SCOUT
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01UnderstandInterpret objective + constraints
02PlanBuild a testable in silico research program
03ExecuteRun computational work across scientific pipelines
04CritiqueChallenge evidence before lab validation
Literature + knowledge
Target / pathway analysis
Structure + docking
Developability / ADMET
Virtual screening / design
CITED · AUDITABLE OUTPUTScout research report readyEvidence · methods · contradictions · unknowns · next steps
100% traceable
SCIENTIFIC + TECHNOLOGY PARTNERS
Schrödinger
OpenEye Scientific
Elsevier
Amazon Web Services
NVIDIA
Cadence
Schrödinger
OpenEye Scientific
Elsevier
Amazon Web Services
NVIDIA
Cadence
Autonomous science in action

Not another AI that stops at an answer.

Scout turns a question into an in silico scientific program. Ask in natural language. Scout determines what work is required, runs the right computational pipelines, critiques the evidence and returns a cited report,helping your team learn earlier, before committing time and cost to physical experiments.

SCOUT · LIVE RESEARCH PROGRAM● running
Sigmatic Scout user interface showing a research question and multi-turn scientific pipeline execution
Natural-language questionScientist asks. Scout interprets.
Multi-step executionTools and analyses run as a program.
Traceable workflowEvery step stays visible and reviewable.
ACHIEVE LAB-IN-THE-LOOP

Close the Loop.
Accelerate Discovery.

Scout proposes. SigmaticOS orchestrates. Scientists guide. The lab validates. Results return to Scout—so every cycle gets smarter.

SCOUT
S

Your AI scientist

Ask a research question in natural language and start an in silico research program.

QUESTION RECEIVED
SIGMATICOS

Orchestrates the science

PLANDefine the research path
ROUTESelect models, data & tools
RUNExecute analyses
LEARNCritique and refine
ORCHESTRATES ACROSS
MODELSDATAAGENTSTOOLS
SCIENTIST IN THE LOOP

Scientists guide the work

Review evidence, add context, challenge conclusions, and decide what moves forward.

HUMAN REVIEW
WET LAB

Validate what matters

Test the highest-value hypotheses and generate trusted experimental evidence.

EXPERIMENTAL VALIDATION
↻ EXPERIMENTAL RESULTS RETURN TO SCOUTEvidence compounds. Decisions improve. Discovery moves faster.
A Different Class of Scientific AIFrom AI Synthesis → In Silico Execution
Why Scout is different

Synthesis is table stakes.
Running the science isn’t.

Compare the typical capabilities of research agents and AI workbenches with Scout. No competitor names—just the capability gap that matters.

Autonomous research agentsgeneral categoryAI research workbenchesgeneral categorySigmatic Scoutautonomous science
Literature synthesis at scale
Runs its own code & analysis
Cited, reproducible output
Target validation dossierad hocad hoc✓ purpose-built
Clinical & patent landscape (FTO)
Designs novel molecules & proteinstool access only✓ generative by default
Developability & off-target profilingtool access only
Reads your ELN, LIMS & data lake
Ingests wet-lab assay results✓ closes the loop
Trains on your proprietary science
Adversarial critic on every step
Deploys inside your perimetervaries
Why Scout is different

Move more of discovery upstream — before you pay for it at the bench.

In silico research is most valuable when it changes which experiments you choose to run. Scout helps teams explore more possibilities computationally, eliminate weaker paths earlier and send higher-value hypotheses into the lab.

TRADITIONAL DRUG DEVELOPMENT

Physical R&D is slow, expensive and failure-heavy.

10–15years to market

Commonly cited industry range from discovery through approval.

$314M–$4.46Bpublished R&D cost estimates

Published estimates vary materially by methodology, indication and included cost of failure.

~12%clinical-to-approval

Only a minority of candidates entering clinical development ultimately reach approval.

IN SILICO
SHIFTS WORK
UPSTREAM
IN SILICO + AUTONOMOUS SCIENCE

Explore more. Fail earlier. Validate smarter.

Screen virtually firstEvaluate far more candidate ideas computationally before committing synthesis, reagents, instruments or assay time.
Run analyses in parallelLiterature, target, pathway, structure, chemistry and developability work can happen concurrently instead of moving one handoff at a time.
Eliminate weak paths earlierSurface contradictions, low-confidence evidence and downstream risk before scarce wet-lab capacity is committed.
Close the loop with the labMove the most valuable hypotheses to experiment, ingest the resulting evidence and let Scout refine the next research cycle.
EXTERNAL AI-ENABLED DISCOVERY EXAMPLE~9–12 months

A 2026 industry example reported reaching development candidates in roughly nine to twelve months versus about 4.5 years traditionally for that milestone. This is an external company-reported example, not a guaranteed Scout result.

The point is not “AI instead of the wet lab.”

The point is fewer low-value experiments, faster iteration, better use of scientific talent and more learning from every dollar of R&D.

Industry benchmarks shown for context; outcomes vary by program, therapeutic area and workflow. Sigmatic does not guarantee the external benchmark results shown here.

SCOUT EARLY ACCESS

30 days. Free.
Real research.

This isn’t a sandbox or staged demo. Run your own research questions on the real Scout product and evaluate the same research output a paying customer receives.

Start Your Free 30 Days →
30DAYS FREE
YOUR QUESTIONSResearch in plain English
REAL SCOUTFull product, not sample data
REAL OUTPUTComplete cited research reports
NO COSTEvaluate before you license