The Agentic Operating System
for Life Sciences R&D
Orchestrate your entire discovery pipeline—tools, data, LLMs, ML, scientists, and the wet lab—into auditable, automated agentic pipelines.
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Trusted life science solutions
integrated into Sigmatic OS toolbelt
Works with your stack
We have built hundreds of agents for open‑source and commercial tools to ensure streamlined workflows that can easily incorporate your in‑house models and LIMS/ELN. 
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In Silico Alone Is Not Enough
Design end‑to‑end discovery pipelines that combine in‑silico tools, lab automation, and expert review, at the touch of a button — just press ‘Go’
In Silico
Unify chem, molbio and informatics tools like RDKit, docking simulations, ML, LLMs, stats, physics tools, RAG and chem/genomic data sources, along with your own models, into automated, agentic pipelines. Large language models can be enhanced with your internal SOPs, protocols and reference materials, enabling them to deliver accurate, context-aware answers to your scientific questions.
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Lab In the Loop
Trigger wet‑lab workflows directly from a SigmaticOS pipeline. SigmaticOS sends work to your LIMS/ELN or other systems such as screening assays, waits for results, then assesses the results and continues automatically, all while minimizing the friction of data and tool integration. SigmaticOS allows teams to train machine-learning models directly within the platform using their proprietary data — from lab experiments to bioprocessing systems.
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Scientist-In-The-Loop
Queue decisions for domain experts with rich context (structures, poses, scores). Here the scientists can then review results and decide on next steps in the pipeline — expert human judgment where it matters most. The platform also supports specialised AI models for areas such as toxicity, solubility and molecular design, which can be fine-tuned using real laboratory data.
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Why choose SigmaticOS?
One operating system for research & discovery
Orchestrate autonomous in‑silico tools, lab systems, LLMs, scientists, and data sources from one place.
Faster from hypothesis to results
Accelerate your innovation: AI co‑designing, parallel execution, and pre‑built templates with automated execution and orchestration compress weeks and months into hours. SigmaticOS also continues to train your models so pipelines improve with each iteration.
Trusted Scale and Traceability
Every step’s inputs and outputs, and every parameter and decision, are recorded. Agents and pipelines are fully versioned—from draft to production—with a full audit trail.
Your tools, your models
SigmaticOS brings hundreds of proven in‑silico tools and data sources, as well as ready‑to‑use commercial engines. We also make it easy to agentize in‑house models so you can use them in automated pipelines quickly and efficiently seamlessly.
Linking Data to Scientific Insight
Enabling scientists to combine legacy data with newly generated insight in a seamless wet/dry lab loop.
From Copilot to Autopilot
It autonomously designs, runs, and governs complex discovery pipelines that span in‑silico analysis, lab automation, and expert decisions seamlessly — scaling to tens of millions of compounds while keeping scientists in control taking you to move from ‘copilot to autopilot’ and enabling 24/7 science.
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Audit-Ready,
Enterprise-Secure
Deployed in a dedicated AWS VPC and ready to go from day one.
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ISO 27001
21 CFR Part 11‑ready
SSO/SAML
Encryption
Audit logs
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FAQs

Absolutely. Agentize in‑house tools (often in a day or less) and mix them with open‑source or commercial engines inside the same pipeline.

Yes. Sigmatic natively integrates with Sapio LIMS/ELN and can connect to others such as Benchling, Revvity, LabVantage, etc. It triggers assays, waits for results, and continues the plan automatically.

Pipelines can pause at decision gates. Scientists receive queued items with full context (structures, poses, IC50s, notes) and approve or route next steps—fully auditable.

Pipelines parallelize work across steps and datasets. Sigmatic is built to handle very large result sets (e.g., tens of millions of compounds) with responsive browsing and filtering.

Draft vs. production pipelines, agent versioning, parameter capture, approvals, and complete run histories deliver an audit‑ready record.

In your dedicated AWS VPC with encryption in transit/at rest. We can connect to your GPUs as well if you need extra capacity.

SOC 2, ISO 27001, 21 CFR Part 11‑ready, SSO/SAML, RBAC, audit logs, DB replication, and daily snapshots.

Yes. Compute is ready, open‑source tools are pre‑agentized, and commercial engines work with your licenses. You can start running pipelines day 1.

You do. Data stays in your VPC. Sigmatic never claims rights to your assets or results or uses it to train models that we would use other than for you.

Ready to move faster?
See how an agentic pipeline turns your hypothesis into an auditable, lab‑validated candidate list.
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The agentic operating
system for life sciences R&D​
Sigmatic OS
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